Introduction: Spirituality is considered as an important issue not only in organizations but also in everyday life. This study aimed to analyze the role of spiritual intelligence in the productivity of employees at Isfahan University of Medical Sciences.

Methods: This applied, descriptive- correlation study was conducted in 2014. The population consisted of 900 people including all finance staff and managers of Isfahan University of Medical Sciences. King questionnaire (version 2008) was used to collect data on spiritual intelligence and a researcher developed questionnaire was used to measure productivity. Data were analyzed using structural equation modeling techniques, descriptive statistics, SPSS software (version 19) and LISREL.

Results: The ratio of LISREL output, 0.48, indicated a good model fit and a t-value of 5.04 confirmed the effectiveness factor. The results showed that t- values of variables were greater than 1.96 which indicates a positive and significant impact of spiritual intelligence on the productivity of employees.

Conclusion: The enhancement of productivity can be achieved through reinforcing spiritual intelligence of employees.