Introduction: In any organization, manpower is the most important element in the improvement and development of that organization and the main factor in achieving the predicted objectives. Job satisfaction not only plays a significant role in achieving organizational objectives it also playas a significant part in the health of individuals as well as the society, thus the influencing factors must be examined by the administrators to correct the pitfalls and reinforce the strengths through careful recognition of opportunities and threats. The objectieve of the present study aimed to reach that end. 

Methods: The present study is a descriptive - analytical type performed on 324 randomly selected personnel of Birjand University of Medical Sciences. Job description index was used as the instrument for collecting. Data were Analyzed by Analysis of variance (ANOVA) and k2 using SPSS software.

Findings: The findings indicate that there is a significant relationship between gender, and job satisfaction regarding promotion system and salary (P<0.05). There was also a significant relationship between the personnel with different educational backgrounds in five job types. Personnel with degrees higher than bachelor were more satisfied with their jobs and salaries. Theses people, however, showed less satisfaction with their supervisors, colleagues, and the promotion system. A meaningful relationship was also observed between employee rank and job satisfaction the most dissatisfied groups regarding salary payments were health care treatment groups.

Results:Taking in to consideration the results of the study indicate that several modification must take place in order to see changes in the attitude of employees towards job satisfaction they include: Reform in the evaluation system, salary system, plans and strategies to correct negative attitude to Jobs, closer boss employee relations and finally long term precise planning can be used as and efficient instrument.