Introduction: Nowadays, higher education has transformed as dynamic and complicated academic ac- tivity, soit’s required for university managersto grasp exact and deep knowledge, and understanding about university circumstances, to effectiveness of university management. This research was aimed to iden- tify circumstances and evaluation of organization through internal and external analysis in case School of Management and Medical Information Science, Isfahan University of Medical Sciences in the year 2007.

Methods: This is a descriptive - survey research, combined with qualitative method. The research population including all of provide chancellors and managers of this university. The data collecting tools are interviews and researcher-made questionnaires. For data analyzing we used qualitative analysis (SWOT), and descriptive statistics methods.

Results: Findings showed that the school have more strength points and opportunities than weaknesses or threat points. So we can use more of opportunities in the way of reduce of weakness. Of course cultural part in this collage has the most weakness. From the collage problems, we can point to the management strong challenges, high concentration in management of university, lack of thinking and invest attitude to the school. 

Conclusion: School of Management and Medical Information Science is in a good situation, and could use external and internal environmental factors appropriately. But still it is face to many problem needs strategic planning and prospect looking, and exploiting strengths and opportunities.