Introduction: In the new millennium people face many serious challenges in health care, including an upward trend in non contagious diseases. Cardiovascular diseases, cancer, and diabetes have had a bigger share respectively. Since cancer mostly develops (come on ) in later life considering the young population of our country and an increase in life expectancy, there is an anticipation that the development of this disease would be on the rise with great momentum. Despite promising trend in improving many aspects of health care and treatment in the last decade in our international standard. Effective practical research specially in etyology, materialization of preventive measures, screening programs in the country's healthcare and treatment policy and the evaluation of the efficiency of their strategies would materialize when the national cancer registration policy is established and it's data are collected and completed to date. The purpose of this comparative cross sectional survey was to study the national cancer registration system of England, Denmark, Malaysia and Iran Propose a suitable model for Iran in the year 2003-4.

Methods: foreign and domestic specialists, as well as library and internet were consulted then the national cancer registration system of England, Denmark and Malaysia were evaluated. Taking into consideration the economical, cultural and geographical condition of the country. A model was suggested with the help of Delfy approach . Athree phase model trial was projected For the first and second phase a question was prepared and the third stage of this trial was carried out in session with the participation of specialists to evaluate. The third model and after analytical work, the final model was presented.

Findings: Research findings the reduction of costs reveal that in order to optimize cancer registration and including data elements, registration criteria, information gathering process, classification and control mechanism of the current national cancer registration should be reevaluated, the results of comparison of proposed model is shown in two diagrams.

Results: Strengthening administrators, enriching corporate culture, promoting creativity and learning, rendering services based on need assessment and client's expectations, along with the client's satisfaction should be taken into consideration.