Introduction: There are more than 700 biochemistry tests that includes one third of laboratory tests. Managing produced information needs to information systems. Present research was aimed to analyze situation of biochemistry information systems in educational-therapeutic hospital laboratories of Shahid Beheshti University of Medical Sciences and Health Services.

Methods: In this descriptive -applied 13 Biochemistry Information Systems of hospital laboratories are reviewed. The sampling method is as census, and data were gathered through observing and questioning by a checklist and a questionnaire. Data are processed and analyzed as descriptive statistics.

Results: We found 76.92% 0f Chemistry Information Systems were stand alone and 23.08% connected to Hospital Information Systems. In these systems, the patients, specimen and biochemical tests data were gathered. Despite being in all systems, data were gathered by test request forms, labels, and computers. In order to process data, the data processing software and auto-analyzers were used, and in 100% of systems, information distribution was done by report forms and computers. In 78.46% of systems, had responsible managers for data gathering, processing and distributing information. None of them didn't have any documented instructors in related of biochemistry department relations with other departments and security of data and informations. 

Discussion: In these systems often focused on those data and activities involved in daily works of wards and laboratories. Laboratories equipped completely by advanced technologies would be better to response to users’ needs.